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  5. 哺乳婦女補充魚湯增加血清中EPA、DHA濃度
 
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哺乳婦女補充魚湯增加血清中EPA、DHA濃度

Other Title
Fish soup supplement increases serum EPA and DHA concentrations in breastfeeding women
Type
thesis
Date Issued
2011-06-29
Author(s)
葉怡妙
Advisor
謝榮鴻
Subjects
系所名稱:保健營養學研究所
Description
學位別:碩士
語文別:中文
指導教授:謝榮鴻
共同指導教授:
口試委員:曾啟瑞;趙湘台
中文關鍵字:二十碳五烯酸;二十二碳六烯酸;三酸甘油酯;母乳
Abstract
二十碳五烯酸(Eicosapentaenoic acid, EPA)及二十二碳六烯酸(Docosahexaenoic acid, DHA)屬於ω-3脂肪酸,近年來許多研究指出EPA及DHA對於孕婦之生理狀況、產婦乳汁組成、產後身心健康、及新生兒成長,或降低血脂及預防冠心病,都有正面的影響。本研究目的在探討產婦補充魚肉及湯後,對於血液脂質變化、生化數值及發炎相關激素變化的影響,同時也檢測母乳中脂肪酸組成及含量,以瞭解產婦攝食狀況對乳汁成分的影響。本實驗經人體試驗委員會同意執行,於台北醫學大學附設醫院婦產科招募受試者,總計二十四位健康哺乳婦女於產後一個月內,連續14天每日補充一次固定份量之魚肉及湯,每份量含有60 g魚肉及100 g魚湯,可提供2.59 g DHA及0.27 g EPA。在受試者補充前、連續補充14天後、停止補充14天後,分別收集10 ml血液及20 ml乳汁,測量其EPA、DHA含量、生化數值及血脂組成,以比較個體本身於實驗介入前後的差異。
結果顯示受試者在未補充魚湯包前血液中EPA百分比濃度為0.5 ± 0.4 % ,連續攝取14天後,血液中EPA百分比濃度顯著上升為1.3 ± 0.7 % (p <0.05),停止補充魚湯包後,也顯著高於未補充魚湯包時血液中EPA百分比濃度 (0.7 ± 0.5 %, p <0.05)。而未補充魚湯包前母乳中EPA百分比濃度為0.1 ± 0.1 %,連續攝取14天後,母乳中EPA百分比濃度顯著上升為0.4 ± 0.2 % (p <0.05),而母乳中DHA百分比濃度在未補充魚湯包前0.7 ± 0.2 % ,連續攝取14天後,DHA百分比濃度也顯著上升為1.7 ± 0.7 % (p < 0.05),同樣地,血液中DHA百分比濃度在未補充魚湯包前為2.5 ± 0.9 %,連續攝取14天後,血液中DHA百分比濃度也顯著上升為3.5 ± 1.6 % (p <0.05)。在血脂質方面,未補充魚湯包前血液中三酸甘油酯為140.9 ± 104.5 mg/dL,連續攝取14天後,血液中三酸甘油酯顯著下降為65.56 ± 29.69 mg/dL (p < 0.05)。在C-反應蛋白方面,在未補充魚湯包前濃度為1.25 ± 1.25,連續攝取14天後其濃度顯著降低為0.12 ± 0.12 (p < 0.05)。於攝取魚湯包前後之生理功能比較,其產婦之腎功能、肝功能及血糖值以及血液常規方面檢查皆無任何影響。
本實驗結果指出每日適量補充魚肉及湯可提高哺乳婦女血液及乳汁中EPA及DHA濃度,且有助於產後降低血液中三酸甘油酯。綜合本實驗結果,補充魚湯包對於哺乳婦女本身以及吸吮乳汁的嬰兒而言都具有正面效益。經飲食問卷分析亦顯示參與本實驗的多數哺乳婦女,攝取較少富含ω-3脂肪酸的飲食,補充魚製品有助於提升其ω-3脂肪酸攝取量。
URI
https://203.71.86.71/handle/123456789/13484

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