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  5. 藥師介入對於愛滋病感染者服藥順服性及用藥安全的影響
 
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藥師介入對於愛滋病感染者服藥順服性及用藥安全的影響

Other Title
The Impact of Pharmacist’s Interventions on Human Immunodeficiency Virus Infected Patients’ Adherence and Drug Safety
Type
thesis
Date Issued
2011-07-05
Author(s)
楊欣瑜
Advisor
簡淑真
Subjects
系所名稱:藥學研究所
Description
學位別:碩士
語文別:中文
指導教授:簡淑真
共同指導教授:
口試委員:河蘊芳;陳世銘
中文關鍵字:藥師;人類免疫缺乏病毒;高效能抗愛滋病毒治療;藥品持有率
Abstract
國內外文獻皆證實高效能抗愛滋病毒治療(highly active antiretroviral therapy, HAART)降低了愛滋病感染者的死亡率,使愛滋病轉變為一種慢性疾病。高效能抗愛滋病毒治療需達到95%以上的服藥順服性以減少病毒學失敗率,然而不同文獻卻指出愛滋病發病者的實際服藥順服性只有40-93%。本研究旨在評估藥師介入對愛滋病感染者服藥順服性及用藥安全的影響
研究醫院從2009年2月5日開始提供愛滋病感染者醫療服務,目前門診愛滋病感染者已達235位,其中83位正在接受高效能抗愛滋病毒治療。本研究從2010年9月15日至2011年5月31日,在研究醫院納入年滿十八歲且初次或正在接受HAART之愛滋病感染者。研究期間共29位個案納入研究分析,藥師主動提供藥事服務後,依藥品持有率(medication possession ratio, MPR)評估愛滋病感染者服藥順服性、同時評估用藥正確知識,並記錄潛在藥物交互作用及藥物不良反應。
本研究顯示藥師介入後,愛滋病感染者服藥順服性、用藥正確知識程度皆有顯著改善,且降低潛在藥物交互作用、副作用的發生率。
URI
https://203.71.86.71/handle/123456789/13676

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