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  5. 輸尿管結石與子宮體惡性腫瘤相關性之研究
 
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輸尿管結石與子宮體惡性腫瘤相關性之研究

Other Title
Relationship between Ureteral Calculus and Uterine Cancer
Type
thesis
Date Issued
2014-07-07
Author(s)
郭嘉駿
Advisor
林恆慶
Subjects
系所名稱:醫務管理學研究所
Description
學位別:碩士
語文別:中文
指導教授:林恆慶
共同指導教授:
口試委員:陳欽賢;郭乃文
中文關鍵字:輸尿管結石;子宮體惡性腫瘤;發炎
Abstract
背景:根據統計尿路結石的發生率逐年上升,帶來急性疼痛及反覆性發作;近年來的研究顯示慢性發炎與癌症相關性密不可分,而骨盆腔內子宮體惡性腫瘤的發生率及死亡率持續增加,故本研究了解輸尿管結石與子宮體癌症關聯。
目的:探討罹患輸尿管結石的女性病患與後續子宮體惡性腫瘤相關性。
方法:本研究採回溯性世代研究,經由國家研究院全民資料庫中2000年承保抽樣歸人檔(LHID2000),分析2001年1月1日至2004年12月31日期間診斷為輸尿管結石的女性病患共有5469位,抽樣取得27345位對照組,每一位病患追蹤五年,以評估罹患輸尿管結石後是否與發生子宮體癌症有相關性。
結果:本研究中每十萬人的子宮體癌年發生率在輸尿管結石的實驗組為7.40 (95% 信賴區間為4.70~11.12),在對照組則為3.38(95% 信賴區間為2.52~4.45);經由stratified Cox proportional regression運算得知,患有輸尿管結石的病患比起對照組有2.21倍(95% 信賴區間為1.29~3.80,p < 0.01) 罹患子宮體癌的風險。輸尿管結石、肥胖、子宮內膜囊狀增生及高血脂症均為罹患子宮體惡性腫瘤共病因子
結論:經由資料庫的分析輸尿管結石的女性病患,追蹤發現罹患子宮體惡性腫瘤的風險較沒有尿路結石的群體高。
URI
https://203.71.86.71/handle/123456789/56796

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