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Association between Multiple Sclerosis and Erectile Dysfunction: A Nationwide Population-based Case-Control Study
Other Title
Association between Multiple Sclerosis and Erectile Dysfunction: A Nationwide Population-based Case-Control Study
Type
thesis
Date Issued
2012-06-15
Author(s)
柯捷
Advisor
梁有志
Subjects
系所名稱：醫學檢驗暨生物技術學系
Publisher
醫學檢驗暨生物技術學系
Description
學位別：碩士
語文別：英文
指導教授：梁有志
共同指導教授：林恆慶
口試委員：陳欽賢;黃昭淵;劉俊仁
中文關鍵字：多發性硬化症;勃起障礙
語文別：英文
指導教授：梁有志
共同指導教授：林恆慶
口試委員：陳欽賢;黃昭淵;劉俊仁
中文關鍵字：多發性硬化症;勃起障礙
Abstract
ABSTRACT
Title of Thesis：Association between Multiple Sclerosis and Erectile Dysfunction: A Nationwide Population-based Case-Control Study
Author：Joseph Keller
Thesis advised by：Yu-Chih Liang, Ph.D. and Herng-Ching Lin, Ph.D.
Introduction: Multiple sclerosis (MS) is an inflammatory disorder of the brain and spinal cord that proceeds through the demyelination of the central nervous system. While a chronic disease, MS commonly affects young adults who may be sexually active, with sexual dysfunction being a significant, but often underestimated, symptom of multiple sclerosis. However, no large-scaled study has investigated the association between erectile dysfunction (ED) and MS in an Asian population to date.
Aim: This study aimed to estimate the association between ED and a prior diagnosis of MS using a population-based dataset with a case-control design in Taiwan.
Methods: We identified 38,139 patients with ED as cases and randomly selected 262,848 subjects as controls. We will then use conditional logistic regression to compute the odds ratio (OR) for having previously received a diagnosis of MS between cases and controls.
Main outcome measure: The prevalence and odds of having been previously diagnosed with MS between cases and controls.
Title of Thesis：Association between Multiple Sclerosis and Erectile Dysfunction: A Nationwide Population-based Case-Control Study
Author：Joseph Keller
Thesis advised by：Yu-Chih Liang, Ph.D. and Herng-Ching Lin, Ph.D.
Introduction: Multiple sclerosis (MS) is an inflammatory disorder of the brain and spinal cord that proceeds through the demyelination of the central nervous system. While a chronic disease, MS commonly affects young adults who may be sexually active, with sexual dysfunction being a significant, but often underestimated, symptom of multiple sclerosis. However, no large-scaled study has investigated the association between erectile dysfunction (ED) and MS in an Asian population to date.
Aim: This study aimed to estimate the association between ED and a prior diagnosis of MS using a population-based dataset with a case-control design in Taiwan.
Methods: We identified 38,139 patients with ED as cases and randomly selected 262,848 subjects as controls. We will then use conditional logistic regression to compute the odds ratio (OR) for having previously received a diagnosis of MS between cases and controls.
Main outcome measure: The prevalence and odds of having been previously diagnosed with MS between cases and controls.