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  5. 魚類攝取與糖尿病患者腎功能之相關性
 
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魚類攝取與糖尿病患者腎功能之相關性

Other Title
Relationship between dietary fish intake and renal function in diabetes patients
Type
thesis
Date Issued
2013-06-17
Author(s)
林詩萍
Advisor
李信昌
Subjects
系所名稱:保健營養學研究所
Description
學位別:碩士
語文別:中文
指導教授:李信昌
共同指導教授:施純光
口試委員:葉松鈴;許青雲;穆淑琪
中文關鍵字:糖尿病腎病變、微蛋白尿、蛋白尿、長鏈n-3脂肪酸、魚類
Abstract
根據衛生署 2011 年統計顯示糖尿病及腎臟疾病於國人十大死因為第四及第十位,並且2012年美國腎臟資料登錄系統 ( United States Renal Data System, USRDS )統計資料顯示台灣末期腎病 (End-stage renal disease, ESRD)盛行率為全球之冠,其中以糖尿病所引發之腎病變為末期腎病主因之ㄧ。文獻指出長鏈n-3脂肪酸補充劑可延緩腎病進展,研究中發現以n-3長鏈脂肪酸介入糖尿病患者發現與降低尿蛋白排出量具有相關性,而流行病學文獻指出補充n-3長鏈脂肪酸對於預防及延緩慢性腎病仍具爭議。本研究目的以食物攝取頻率問卷觀察糖尿病腎病變患者與長鏈n-3脂肪酸及魚類攝取量,並探討上述攝取量對腎功能指標之影響。結果顯示:腎病變組受試者低脂、中脂、高脂魚類攝取量顯著低於糖尿病組,而n-3長鏈脂肪酸攝取量兩組間無顯著差異,而高脂魚類攝取與腎功能指標中肌酸酐呈現負相關 (r= -0.168, P= 0.044)。邏輯斯迴歸分析顯示低脂、中脂及高脂魚類對糖尿病腎病變之勝算比分別為0.768 (P= 0.029),0.743 (P= 0.014)及0.733 (P= 0.006),表示增加低脂、中脂及高脂魚類攝取有助降低罹患腎病變風險。結論:經由膳食問卷調查分析魚類攝取量與降低糖尿病腎病變罹病風險具相關性。
URI
https://203.71.86.71/handle/123456789/13817

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