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  5. 石花菜對餵予高膽固醇飲食SD大鼠脂質代謝之影響
 
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石花菜對餵予高膽固醇飲食SD大鼠脂質代謝之影響

Other Title
Effects of Gelidium amansii on lipid metabolism in SD rats fed with high cholesterol diet
Type
thesis
Date Issued
2011-07-18
Author(s)
蔡孟融
Advisor
陳玉華
Subjects
系所名稱:保健營養學研究所
Description
學位別:碩士
語文別:中文
指導教授:陳玉華
共同指導教授:
口試委員:楊素卿;劉承慈
中文關鍵字:石花菜;高膽固醇飲食;脂質代謝;血液脂質;肝臟脂質
Abstract
高脂血症是目前台灣高盛行率的一種疾病,其與血管相關疾病關係密切,因此若能藉由飲食控制脂質代謝以避免高脂血症,可能可降低許多相關疾病的發生。文獻指出海藻具調控脂質代謝之作用,其中石花菜 (Gelidium amansii, Ga)為生長於台灣東北角之紅藻,雖傳言其具不同功能如減重、降血脂等,但相關科學文獻有限,故本實驗利用動物模式來探討Ga對於血脂調控之影響。在以AIN-76為基礎的高膽固醇飲食 (1 %)餵予SD大鼠的同時,於飲食中補充低 (2%)、中 (5%)和高 (8%)三種劑量的Ga乾燥粉末,經餵食十週後測量大鼠血液、肝臟與糞便中的脂肪相關指標。結果顯示在高膽固醇飲食與2 %與8 %石花菜同時介入下,具提高血液總膽固醇、血液三酸甘油酯和極低密度脂蛋白膽固醇濃度,8 %石花菜亦同時提高血清高密度脂蛋白膽固醇濃度,5 %石花菜則增加肝臟總膽固醇含量。因此乾燥石花菜粉末的給予,可使餵予高膽固醇飲食之SD大鼠提高血清膽固醇與三酸甘油酯濃度,同時亦會使肝臟膽固醇含量增加。
URI
https://203.71.86.71/handle/123456789/13488

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