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  5. 探討抗生素治療急性單純性闌尾炎的復發率及其相關影響因子
 
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探討抗生素治療急性單純性闌尾炎的復發率及其相關影響因子

Other Title
The recurrence and impact factor of acute simple appendicitis with antibiotic therapy
Type
thesis
Date Issued
2017-06-05
Author(s)
周姵環
Advisor
林恆慶
Subjects
系所名稱:醫務管理學研究所
Description
學位別:碩士
語文別:中文
指導教授:林恆慶
口試委員:陳欽賢;郭乃文
中文關鍵字:急性闌尾炎;抗生素治療;非手術治療
英文關鍵字:Acute appendicitis;antibiotic therapy;alternative therapy
Abstract
研究目的:急性闌尾炎臨床治療多以闌尾切除手術進行,抗生素治療急性單純性闌尾炎對患者是一種非侵入性的替代療法。本研究旨在探討抗生素治療單純性闌尾炎的復發率與相關影響因子,藉以區分適合抗生素治療的患者族群。

研究方法:本研究資料來源為『全民健康保險資料庫』(LHID2005)的兩百萬承保抽樣歸人檔。以2005年至2012年資料庫篩選出抗生素治療急性闌尾炎患者為分析對象,選取ICD-9-CM codes 540及540.9無併發症的單純性闌尾炎患者,排除540.0、540.1及541等複雜性闌尾炎相關疾病。

研究結果:充血性心衰竭患者接受抗生素治療急性闌尾炎的復發風險,是非充血性心衰竭患者的3.06倍(風險比=3.06,95%信賴區間=1.33-7.06,P≤0.01)。

結論:本研究結果發現,充血性心衰竭患者接受抗生素治療急性單純性闌尾炎,一年內有較高的闌尾炎復發風險,在統計上有顯著差異。台灣地區抗生素治療急性闌尾炎與慢性病相關研究較為不足,但抗生素治療急性闌尾炎對患者有諸多益處,本研究結果顯示,除去充血性心衰竭的患者外,多數慢性病患者在抗生素治療風險不高。因此,建議外科醫師臨床治療單純性闌尾炎可考慮抗生素治療取代闌尾切除手術,避免經由闌尾切除手術對患者的免疫系統造成破壞,面對癌症潛在的威脅,健康的闌尾是在淋巴與免疫系統中相當重要,應盡力保全闌尾器官以維護患者健康的最大權益。
URI
https://203.71.86.71/handle/123456789/57850

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