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  3. .博碩士學位論文
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  5. 探討心率變異性、神經功能和臨床因素對缺血性中風病人死亡率與行為功能預後之關係
 
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探討心率變異性、神經功能和臨床因素對缺血性中風病人死亡率與行為功能預後之關係

Other Title
Exploring Relationships of Heart Rate Variability, Neurological Function, and Clinical Factors with Mortality and Behavioral Functional Outcome in Patients with Ischemic Stroke
Type
thesis
Date Issued
2024-07-04
Author(s)
吳美容
Advisor
林明錦
Subjects
系所名稱:醫學資訊研究所博士班
Publisher
醫學資訊研究所博士班
Description
學位別:博士
關鍵字:缺血性中風; 心率變異性; 死亡率; NIHSS; mRS; 功能預後
論文公開日期:2024-07-25
Abstract
缺血性中風是導致死亡和殘疾的主要原因。心率變異(HRV)與中風相關因素對死亡率和行為功能預後的關係是複雜且尚未完全理解。瞭解這些關係對於更好地預測缺血性中風預後極為重要。本研究目的是探討心率變異性、神經功能和臨床因素與缺血性中風病人的死亡率及3個月行為功能預後之間的關係。本研究以前瞻性設計收集心率變異性參數,並監測缺血性中風病人的行為功能預後。行為功能預後以改良Rankin量表(mRS)評分表示。本研究對象包括58名缺血性中風病人(56.9%為男性;平均年齡70.9±13.31歲),其中有良好結果(mRS評分≤2)和不良結果(mRS評分≥3)。分析顯示, R-R間期(RR interval)平均值的中位數在存活組與死亡組之間沒有統計上顯著差異。RR mean的中位數與不良結果組(unfavorable)具統計上顯著相關(OR== 0.989,p = 0.007)。較低的血紅蛋白數值與不良結果組(unfavorable)具顯著相關(OR = 0.411,p = 0.010)。相反,入院時神經功能由NIHSS評分測量與死亡率沒有顯著相關。入院時較高的NIHSS評分與不良結果(unfavorable)顯著相關(OR = 1.396,p = 0.002)。年齡、中風史、入院時的NIHSS評分和血紅蛋白數值與缺血性中風的死亡率無顯著相關。這些結果顯示,HRV(以RR mean的中位數表示),及特定臨床因素和入院時的神經功能(由NIHSS評分測量),可能作為缺血性中風病人3個月行為功能結果的潛在預後指標。
URI
https://203.71.86.71/handle/123456789/9960

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