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  5. 以健保資料庫與癌症登記檔分析糖尿病患者使用胰島素治療罹患癌症之風險
 
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以健保資料庫與癌症登記檔分析糖尿病患者使用胰島素治療罹患癌症之風險

Other Title
Using NHIRD and Taiwan Cancer Registry to Analyze the Relationship Between Insulin and the Risk of Cancer with Diabetes
Type
thesis
Date Issued
2016-06-30
Author(s)
王詩婷
Advisor
邱泓文
Subjects
系所名稱:醫學資訊研究所
Description
學位別:碩士
語文別:中文
指導教授:邱泓文
共同指導教授:
口試委員:邵于宣;林秀立
中文關鍵字:全民健保資料庫;糖尿病;胰島素;癌症;卡方檢定;邏輯斯迴歸分析;存活分析
英文關鍵字:NHIRD;Diabetes Mellitus(DM);Insulin;Cancer;Chi-square test;Logistic Regression;Cox Regression
Abstract
動機:糖尿病與癌症有高度的相關性。目前研究指出,糖尿病患者中使用胰島素治療者會增加其罹癌的風險。

目的: (1)評估糖尿病患使用胰島素治療者使用在罹癌風險上是否大於沒有使用胰島素治療者。(2)評估使用胰島素時間大於兩年者在罹癌風險上是否高於使用時間小於兩年者。

方法:藉由全民健康保險研究資料庫找出糖尿病患使用胰島素治療並且罹患癌症之研究對象。研究將分為實驗組以及對照組,實驗組為使用胰島素且罹癌之病患,對照組為沒有使用胰島素但罹癌之病患,並利用卡方檢定算出其因素與癌症之間關聯分析之結果。

結果:無法證實在追蹤時間五年內,使用胰島素治療的糖尿病患相較於沒有使用胰島素治療的病患有較高的罹癌風險。在追蹤時間五年內,使用胰島素治療時間大於兩年者者與胰島素治療時間小於兩年者相比,沒有較高的罹癌風險。
URI
https://203.71.86.71/handle/123456789/57600

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