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  5. 紅鳳菜對於糖尿病前期患者血糖控制和抗氧化能力的影響
 
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紅鳳菜對於糖尿病前期患者血糖控制和抗氧化能力的影響

Other Title
Effects of Gynura bicolor on Glycemic Control and Antioxidant Ability in Prediabetes
Type
thesis
Date Issued
2014-06-20
Author(s)
夏竹萱
Advisor
簡怡雯
Subjects
系所名稱:保健營養學研究所
Description
學位別:碩士
語文別:中文
指導教授:簡怡雯
共同指導教授:
口試委員:劉珍芳;楊素卿
中文關鍵字:紅鳳菜;糖尿病前期;植化素;血糖;氧化壓力
Abstract
美國糖尿病學會(american diabetes association, ADA)將血糖值高於標準值但尚未達到診斷標準的族群定義為「糖尿病前期」。若能及早於糖尿病前期時改善其血糖值,可降低罹患糖尿病或併發症的風險。本次實驗的目的為給予糖尿病前期患者每日飲食中含2份紅鳳菜,觀察對於血糖控制和抗氧化能力之影響。共進行12週的試驗,實驗期8週,排空期4週,選入的受試者依照年齡和體位測量數據分為控制組和實驗組,所有受試者於第0 週、第8週及第12週進行體位測量和抽取靜脈血液進行生化檢驗(血糖、血脂、肝腎功能及抗氧化指標等),此外於第0週和第8週給予75克葡萄糖進行口服葡萄糖耐受性試驗(測驗第0、30、60、90、120分鐘的血糖值)、皮膚抗氧化力檢測(彈性和水分散失測試)及繳交三日飲食紀錄(兩天平日,一天假日)。兩組皆給予糖尿病飲食計畫與衛教,依受試者體型和活動量進行個別指導。實驗組每日飲食中含2份紅鳳菜,避免攝取其他紅紫色食物(如:紫米、紅豆、紫高麗、茄子、葡萄、藍莓等);控制組則教育避免攝取所有紅紫色食物。結果顯示,介入8週後實驗組膳食纖維量顯著增加、空腹血糖值降低、改善胰島素阻抗性指標(HOMA-IR)和敏感度指標(QUICKI),提升總抗氧化能力、血中MDA濃度下降及GSH-Px活性上升,推論紅鳳菜因其含有膳食纖維和多酚類使空腹血糖值降低、體內氧化壓力降低進而達到改善胰島素阻抗性和提升胰島素敏感度,可預防發展為第2型糖尿病。
URI
https://203.71.86.71/handle/123456789/56735

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