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  5. 金奈米棒結合金屬性二硫化鉬奈米層片於光誘導抗菌之應用
 
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金奈米棒結合金屬性二硫化鉬奈米層片於光誘導抗菌之應用

Other Title
Gold nanorods decorated metallic MoS2 nanosheets for light-induced antibacterial application
Type
thesis
Date Issued
2023-01-11
Author(s)
王伯峰
Advisor
陳志華 ; 郭聰榮
Subjects
系所名稱:生醫光機電研究所碩士班
Description
學位別:碩士
語文別:中文
口試委員:陳志華 CHEN,CHIH-HWA ;郭聰榮 Kuo, TSUNG-RONG;莊爾元 Chuang,ER-YUAN ;范育睿 Fan ,YU-JUI;楊正昌 Yang, JEN-CHANG
授權範圍:網際網路,開放日期為2023-01-30
Abstract
背景:光響應奈米複合材料在生物醫學領域的抗菌應用中變得越來越有吸引力。
方法:合成了可見光激活的金屬二硫化鉬奈米片 (1T-MoS2 NSs) 和在 808 nm 波長處吸收的等離子體金奈米棒 (AuNRs)。通過靜電吸附成功製備了裝飾在 1T-MoS2 NSs 上的 AuNR 奈米複合材料(MoS2@AuNRs),用於光療應用。
結果:基於光熱效應,在 808 nm 近紅外 (NIR) 照射 10 分鐘後,MoS2@AuNR 奈米複合材料的溶液溫度從 25 ºC 增加到 66.7 ºC。對於光動力效應,MoS2@AuNR 奈米複合材料在可見光照射下產生活性氧 (ROS)。通過瓊脂平板計數證實了 MoS2@AuNRs 的光熱療法和光動力療法可以對抗大腸桿菌。最重要的是,與光熱療法或光動力療法相比,MoS2@AuNR 奈米複合材料的光熱療法和光動力療法的組合顯示出更高的抗菌活性。
結論:光活化的 MoS2@AuNR 奈米複合材料表現出顯著的光熱療法和光動力療法的協同作用,為對抗細菌感染提供了一種替代方法。
URI
https://handle.ncl.edu.tw/11296/tcxah6
https://203.71.86.71/handle/123456789/10388

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