Comparing Mean and Directional Diffusivity in Human Ischemic Stroke

We present a study which compared DWI and DTI study in ischemic stroke with four different parameters: apparent diffusion coefficient (ADC), scaled relative anisotropy (sRA), axial diffusivity (AD) and the radial diffusivity (RD). We found the ADC and AD are significantly decreased in acute/subacute cases. RA and RD show the same trend but not statistically significant. In conclusion, axial diffusivity is comparable to ADC. DTI could potentially provide a quantitative biomarker to evaluate the ischemic stroke and predict outcome