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  5. 載脂蛋白E在胃癌患者血漿中的轉譯後修飾差異性
 
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載脂蛋白E在胃癌患者血漿中的轉譯後修飾差異性

Other Title
The Differential Expressed Post-translational Modification Signature of Circulating Apolipoprotein E in Plasma of Gastric Cancer Patients
Type
thesis
Date Issued
2014-01-20
Author(s)
廖儷婷
Advisor
林景堉
Subjects
系所名稱:醫學檢驗暨生物技術學系所
Description
學位別:碩士
語文別:中文
指導教授:林景堉
共同指導教授:
口試委員:陳威戎;張哲菖
中文關鍵字:載脂蛋白E;胃癌;轉譯後修飾
Abstract
胃癌是世界盛行的癌症之一,於世界癌症發生率的排名中位居第4位,死亡率位居第2位,而早期診斷是改善胃癌病人長期存活最好的方法,故發現與早期診斷胃癌相關的血漿或血清生物標誌物是非常重要的。在我們的血漿樣本中,為了達到鑑定血漿中微量蛋白質量的變化與不同種類的轉譯後修飾,我們將胃癌病患與其性別年齡配對之健康血漿檢體,利用一維 SDS-PAGE 結合 LC MS/MS 進行分析。在本次報告中,我們在血漿中鑑定到載脂蛋白E在蛋白質表現與轉譯後修飾有顯著差異。
URI
https://203.71.86.71/handle/123456789/56912

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