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抗菌複合薄膜電燒刀裝置於肝臟組織之熱影響研究
Other Title
Research on thermal effect of electrosurgical devices with
anti-adhesion composite films on liver
anti-adhesion composite films on liver
Type
thesis
Date Issued
2013-12-21
Author(s)
陳建富
Advisor
黃瓊芳
Subjects
系所名稱:醫療器材產業碩士專班
Description
學位別:碩士
語文別:英文
指導教授:黃瓊芳
共同指導教授:
口試委員:林利香;歐士輔
中文關鍵字:表面處理;類鑽碳;電燒刀設備;動物實驗
語文別:英文
指導教授:黃瓊芳
共同指導教授:
口試委員:林利香;歐士輔
中文關鍵字:表面處理;類鑽碳;電燒刀設備;動物實驗
Abstract
Abstract
Background: The purpose of this study is to investigate the thermal effect on
the liver resulting from electrosurgical devices with cupper-doped
diamond-like carbon (Cu-DLC) surface treatment using computer aided
analysis and animal models. It is necessary to reduce the thermal damage in
the adjacent tissues for clinical electrosurgical surgeries.
Method: Cu-DLC films were characterized by scanning electron microscope
(SEM) and transmission electron microscopy (TEM) to analyze the surface
morphologies in this study. Bionic liver models were reconstructed using
magnetic resonance image (MRI), and data analysis indicated that the
temperature decreased significantly when using electrosurgical device with
nanostructured Cu-DLC films, temperature also decreased with increasing
film thicknesses.
Results: Lesions were made on the liver of adult rats, and thermography
revealed the surgical temperature in liver tissue from the Cu-DLC group was
significantly lower than the untreated group. Moreover, Cu-DLC electrodes
caused a relatively smaller area of injury area and lateral thermal injury, a
smaller area of fibrotic tissue, and a faster process of wound healing than the
untreated group.
II
Conclusion: Results indicated that the coated film reduced excessive
temperature and transformed the temperature uniformly in the liver tissue.
Background: The purpose of this study is to investigate the thermal effect on
the liver resulting from electrosurgical devices with cupper-doped
diamond-like carbon (Cu-DLC) surface treatment using computer aided
analysis and animal models. It is necessary to reduce the thermal damage in
the adjacent tissues for clinical electrosurgical surgeries.
Method: Cu-DLC films were characterized by scanning electron microscope
(SEM) and transmission electron microscopy (TEM) to analyze the surface
morphologies in this study. Bionic liver models were reconstructed using
magnetic resonance image (MRI), and data analysis indicated that the
temperature decreased significantly when using electrosurgical device with
nanostructured Cu-DLC films, temperature also decreased with increasing
film thicknesses.
Results: Lesions were made on the liver of adult rats, and thermography
revealed the surgical temperature in liver tissue from the Cu-DLC group was
significantly lower than the untreated group. Moreover, Cu-DLC electrodes
caused a relatively smaller area of injury area and lateral thermal injury, a
smaller area of fibrotic tissue, and a faster process of wound healing than the
untreated group.
II
Conclusion: Results indicated that the coated film reduced excessive
temperature and transformed the temperature uniformly in the liver tissue.