SANNA, MATTIAFRANCIS NJALA2026-09-092026-09-092026-06-16https://handle.ncl.edu.tw/11296/sz7g4shttps://203.71.86.71/handle/123456789/74267學位別：碩士 語文別：英文 指導教授：SANNA, MATTIA 口試委員：高志文; SANNA, MATTIA; 蔡旻光 授權範圍：網際網路,開放日期為2026-07-06 電子論文連結：https://handle.ncl.edu.tw/11296/sz7g4sBackground: Lung cancer remains the foremost cause of cancer mortality worldwide. Although smoking continues to be the principle risk factor, PM₂.₅ has been identified as an important environmental carcinogen. Despite this, it is unclear whether improvements in PM₂.₅ translate into measurable reductions in lung cancer mortality over time. Aim: To examine the relationship etween long-term PM₂.₅ exposure and lung cancer mortality across OECD countries and Taiwan while accounting for smoking and occupational exposure. Methods: A longitudinal ecological study using panel data from OECD countries and Taiwan was conducted. Descriptive analysis, joinpoint regression, and two-way fixed effects regression with Driscoll–Kraay robust standard errors were applied using lagged exposure models. Results: Lung cancer mortality and PM₂.₅ concentrations generally declined across most countries. Male mortality showed more consistent declines than female mortality. PM₂.₅ and smoking remained positively associated with lung cancer mortality, although smoking contributed the largest proportion to mortality variation (65.8%), followed by occupational exposure (25.8%) and PM₂.₅ (8.4%). Conclusion: PM₂.₅ remains associated with lung cancer mortality despite improving air quality; however, smoking remains the dominant contributor to mortality trends. Integrated strategies combining tobacco control, environmental regulation, and occupational health policies are essential for reducing lung cancer mortality. Key words: Lung cancer mortality; PM₂.₅; smoking; occupational exposure; OECD countries; Taiwan.系所名稱：全球衛生暨衛生安全碩士學位學程thesis