侯文琪Shih CK; Chen SH; Hou WC; Cheng HH2026-05-242026-05-242007https://203.71.86.71/handle/123456789/34604Diabetes mellitus is a common problem in developed countries. An improved postprandial hyperglycemic peak is one of the main therapeutic targets in diabetic patients. The Wistar rats with streptozotocin (STZ)-induced diabetes were divided into cornstarch (control) and Japonica rice groups, which were fed 640 g starch/kg diets for 4 weeks. The area (means ± SD) under the glucose curve of cornstarch was 173.8 ± 6.9 and Japonica rice diet was 154.3 ± 8.7 mmol × min/L, and the area (means ± SD) under the insulin curve of cornstarch was 12.9 ± 0.1 and Japonica rice diet was 12.0 ± 0.6 nmol × min/L. The glycosylated hemoglobin levels, serum fructosamine and cholesterol concentrations in diabetic rats fed the Japonica rice diet were significantly lower than the control group (P < 0.05). The decreased malondialdehyde levels and increased superoxide dismutase activity and total radical-trapping antioxidant parameter in plasma were also found in rat fed the Japonica rice diet compared to the control. These results suggested that the diet containing high-resistance-starch Japonica rice might reduce glycosylated hemoglobin levels, serum cholesterol concentrations and raised the antioxidant status in the blood. Keywords: Antioxidant; Streptozotocin; High-resistance-starch rice; Glycosylated hemoglobin; Total radical-trapping antioxidant parameteren-US生藥學研究所期刊論文article