劉得任Der-Zen LiuSupachok Sinchaikul; Peddiahgari Vasu; Meng-Yang Chang; Shui-Tein Chen;2026-05-222026-05-222007https://203.71.86.71/handle/123456789/28188A novel glucose-conjugated paclitaxel 5 was synthesized using succinic acid as linker between 2'-paclitaxel and methyl 2'-glucopyranose. 5 has not only improved the pharmaceutical properties of paclitaxel, such as solubility and stability, but also enhanced the specific target delivery to MCF-7 cells without the cytotoxicity against normal cells. Therefore, the glucose conjugation may be potentially used in the targeted delivery of other drugs into cells via glucose transporters (GLUTs) for cancer therapyen-US生醫材料暨組織工程研究所期刊論文article