Shio-Shin JeanPo-Ren HsuehWen-Sen LeeHou-Tai ChangMing-Yuan ChouIng-Shen ChenJen-Hsien WangChen-Fu LinJainn-Ming ShyrWen-Chien KoJiunn-Jong WuYung-Ching LiuWen-Kuei HuangLee-Jene TengCheng-Yi Liu2026-05-272026-05-272008https://203.71.86.71/handle/123456789/38558To determine the antimicrobial resistance profiles among clinical isolates of Enterobacteriaceae in Taiwanese intensive care units (ICUs), a national surveillance of antibiotic resistance among important Enterobacteriaceae was conducted from September 2005 through November 2005 at the ICUs of ten major teaching hospitals in Taiwan. A total of 574 Enterobacteriaceae isolates recovered from various clinical samples of our ICU patients were submitted for in vitro test. Minimum inhibitory concentrations (MICs) of these isolates to 18 antimicrobial agents were determined by the broth microdilution method. The prevalences of Enterobacteriaceae isolates with phenotypic extendedspectrum β-lactamase (ESBL) production were 26% in Klebsiella pneumoniae, 16% in Serratia marcescens, 14% in Escherichia coli, and 13% in Proteus mirabilis, in which a significantly rising prevalence of ESBL production among K. pneumoniae was noted (p=0.002) when compared with a previous Taiwanese survey in 2000.81343 bytesapplication/pdfen-US萬芳醫院科部：內科部類別：期刊論文article